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Evidence of SARS-CoV-2 JN.2.5 variant circulation in Rio de Janeiro, Brazil
Mariane Talon de Menezes
Camila Velozo
Filipe Moreira
Diana Mariani
Érica Ramos dos Santos Nascimento
Cassia Cristina Alves Gonçalves
Lídia Theodoro Boullosa
Thaís Felix
Gleidson da Silva de Oliveira
Maria Cecília da Cunha Carneiro
Cinthia Francisca Valdez
Natacha Faria
Bianca Ortiz da silva
Rafael Mello Galliez
Átila Rossi
Carolina Voloch
Terezinha Marta Castineiras
Amilcar Tanuri
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://doi.org/10.1101/2024.04.25.24306286
https://www.medrxiv.org/content/10.1101/2024.04.25.24306286v1
New SARS-CoV-2 variants are continually emerging and have the potential to present challenges to public health responses worldwide. This report discusses the early detection of the lineage JN.2.5 (alias of B.1.1.529.2.86.1.2.5) in Rio de Janeiro, Brazil. The variant was identified in early 2024 through viral whole-genome sequencing and phylogenetic analysis, revealing that circulating strains present genetic similarities to sequences reported in Canada, Poland, Belgium, and England. While the circulation of diverse Omicron sub lineages has significantly impacted COVID-19 epidemiology in Brazil, the consequences of the circulation of the novel variant are uncertain. Considering its immunological escape capabilities and epidemiological behavior observed elsewhere, close monitoring of this variant epidemiology is recommended. Sponsorships This work was supported in part by grants from Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro/FAPERJ (E−26/210.785/2021) and from Instituto Todos pela Saúde/ITpS (C1114/2021). These sponsors had no role in the study design, execution, analysis, interpretation of data, or decision to present the results.
bioRxiv
26-04-2024
Preimpreso
Inglés
Público en general
VIRUS RESPIRATORIOS
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