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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/8548| Pharmacological interventions for COVID-19: Protocol for a Rapid Living Systematic Review with network meta-analysis | |
| Ana Carolina Pereira Nunes Pinto Aline Pereira Rocha Keilla Machado Martins Milby Cesar Ramos Rocha-Filho Felipe Reis Nelson Carvas Junior Vinicius Civile Rodolfo Rodrigo Pereira Santos Giulia Trevisani Laura Jantsch Ferla Gabriel Ramalho Maria Eduarda dos Santos Puga Virginia Trevisani Alvaro Nagib Atallah | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| https://doi.org/10.1101/2020.05.02.20088823 | |
| https://www.medrxiv.org/content/10.1101/2020.05.02.20088823v1 | |
| CONTEXT AND OBJECTIVE Coronavirus disease 2019 (COVID-19) has emerged in China in December 2019 and rapidly spread. Although extraordinary efforts have been made on research regarding pharmacological interventions, none have proven effective. This is the protocol for a rapid living systematic review that aims to compare the effectiveness and safety of different pharmacological interventions for the treatment of COVID-19. METHODS rapid living systematic review methodology with Network Meta-Analysis following the recommendations of Cochrane Handbook. We will include randomized controlled trials (RCT) and quasi-RCTs that evaluate single and/or combined pharmacological interventions at any dose for the treatment of COVID-19. We will search PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), LILACS, Scopus and SciELO to identify potentially eligible studies. No language restrictions will be used in the selection. We will perform the critical appraisal of included studies with the Risk of Bias tool and the certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). | |
| bioRxiv | |
| 06-05-2020 | |
| Preimpreso | |
| Inglés | |
| Público en general | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Materiales de Consulta y Comunicados Técnicos |
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| Pharmacological interventions for COVID-19 Protocol for a Rapid Living Systematic Review with network meta-analysis.pdf | 58.95 kB | Adobe PDF | Visualizar/Abrir |