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Determinants of health-related quality of life in healthy children and adolescents during the COVID-19 pandemic: results from the longitudinal cohort study Ciao Corona
Sarah Haile
Gabriela P Peralta
Alessia Raineri
Agne Ulyte
Milo Puhan
Thomas Radtke
Susi Kriemler
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://doi.org/10.1101/2023.08.25.23294563
https://www.medrxiv.org/content/10.1101/2023.08.25.23294563v1
Abstract Purpose Understanding health-related quality of life (HRQOL) in children and adolescents, during a pandemic and afterwards, aids in understanding how circumstances in their lives impact their well-being. We aimed to identify determinants of HRQOL from a set of biological, psychological and social factors. Methods Data was taken from a longitudinal sample (n = 1843) of children and adolescents enrolled in the prospective school-based cohort study Ciao Corona in Switzerland. The primary outcome was HRQOL, assessed using the KINDL total score and its subscales (each from 0, worst, to 100, best). Potential determinants, including biological (physical activity, screen time, sleep, chronic conditions, etc), psychological (sadness, anxiousness, stress) and social (nationality, parents’ education, etc) factors, were assessed in 2020 and 2021, and HRQOL in 2022. Determinants were identified in a data-driven manner using recursive partitioning to define homogeneous subgroups, stratified by school level. Results Median KINDL total score in the empirically identified subgroups ranged from 68 to 83 in primary school children and from 69 to 82 in adolescents in secondary school. The psychological factors sadness, anxiousness and stress in 2021 were identified as the most important determinants of HRQOL in both primary and secondary school children. Other factors, such as physical activity, screen time, chronic conditions or nationality, were determinants only in individual subscales. Conclusion Recent mental health, more than biological, physical or social factors, played a key role in determining HRQOL in children and adolescents during pandemic times. Public health strategies to improve mental health may therefore be effective in improving HRQOL in this age group. The authors thank Samuel Gunz for his assistance with preparing an earlier version of the HRQOL and lifestyle data used here.
bioRxiv
25-08-2023
Preimpreso
Inglés
Público en general
VIRUS RESPIRATORIOS
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