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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/8169| Phenotypic grouping of Catheter-Associated Escherichia coli from COVID-19 isolation wards using Hierarchical clustering in Surabaya, Indonesia | |
| Daniel Edbert Ni Made Mertaniasih Pepy Dwi Endraswari | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| https://doi.org/10.1101/2023.07.26.23293190 | |
| https://www.medrxiv.org/content/10.1101/2023.07.26.23293190v1 | |
| Introduction Moderate to critical COVID-19 patients may be indicated for urinary catheter use due to the risk of immobility and ventilator or oxygen use. In intensive care units, 18-81.7% of all patients use a urinary catheter. Almost all patients with urinary catheters suffered from bacteriuria within 30 catheter-days. Hospital-associated isolate tracing is mainly performed using complex molecular tests that are not vastly available. This study aims to trace catheter-associated urinary tract infection (CAUTI) isolates using a common hierarchical clustering method that is vastly available Methods This is a descriptive study presenting a collection of Escherichia coli culture data performed by dr. Soetomo Public Hospital microbiology laboratory from March, 26th 2020 to March, 31st 2021. Hierarchical clustering was performed using statistical software using Ward’s clustering method. Results There are 36 E.coli associated with CAUTI. Isolate biochemistry profile and minimum inhibitory concentrations profiles were clustered into 3 clades for each profile. A total of 9 cluster combinations were found. Cluster-ID 1 was melibiose fermenters, Cluster ID 2 was a non-Arginine utilizer, and Cluster ID-3 was an Arginine utilizer. Cluster MIC A consists of third-generation Cephalosporin resistant isolates, Cluster MIC C was multi-susceptible isolates. The Chi-square test between cluster ID and MIC showed no significant differences between the number of isolates per group (X2, p = .430, CI = 95%). Conclusion CAUTI associated E.coli is divided into 9 clusters. This indicates no cluster dominates the isolates, thus CAUTI is not caused by hospital transmission but by normal flora carried by the admitted patient. | |
| bioRxiv | |
| 28-07-2023 | |
| Preimpreso | |
| Inglés | |
| Público en general | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Materiales de Consulta y Comunicados Técnicos |
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