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Health inequalities in SARS-CoV-2 infection during the second wave in England: REACT-1 study | |
HAOWEI WANG Kylie Ainslie Caroline Walters Oliver Eales David Haw Christina Atchison Claudio Fronterrè Peter Diggle Deborah Ashby Graham Cooke Wendy Barclay Helen Ward Ara Darzi Christl Donnelly Steven Riley Paul Elliott | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
https://doi.org/10.1101/2023.08.01.23293491 | |
https://www.medrxiv.org/content/10.1101/2023.08.01.23293491v2 | |
Background The rapid spread of SARS-CoV-2 infection caused high levels of hospitalisation and deaths in late 2020 and early 2021 during the second wave in England. Severe disease during this period was associated with marked health inequalities across ethnic and sociodemographic subgroups. Methods We analysed risk factors for test-positivity for SARS-CoV-2, based on self-administered throat and nose swabs in the community during rounds 5 to 10 of the REal-time Assessment of Community Transmission-1 (REACT-1) study between 18 September 2020 and 30 March 2021. Results Compared to white ethnicity, people of Asian and black ethnicity had a higher risk of infection during rounds 5 to 10, with odds of 1.46 (1.27, 1.69) and 1.35 (1.11, 1.64) respectively. Among ethnic subgroups, the highest and the second-highest odds were found in Bangladeshi and Pakistan participants at 3.29 (2.23, 4.86) and 2.15 (1.73, 2.68) respectively when compared to British whites. People in larger (compared to smaller) households had higher odds of infection. Health care workers with direct patient contact and care home workers showed higher odds of infection compared to other essential/key workers. Additionally, the odds of infection among participants in public-facing activities or settings were greater than among those not working in those activities or settings. | |
bioRxiv | |
03-08-2023 | |
Preimpreso | |
Inglés | |
VIRUS RESPIRATORIOS | |
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