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Global surveillance of novel SARS-CoV-2 variants
Selina Patel
Fergus Cumming
Andre Charlett
Steven Riley
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://doi.org/10.1101/2023.04.10.23288358
https://doi.org/10.1101/2023.04.10.23288358
Earlier global detection of novel SARS-CoV-2 variants gives governments more time to respond. However, few countries can implement timely national surveillance resulting in gaps in monitoring. The UK implemented large-scale community and hospital surveillance, but experience suggests it may be faster to detect new variants through testing UK arrivals for surveillance. We developed simulations of the emergence and importation of novel variants with a range of infection hospitalisation rates (IHR) to the UK. We compared time taken to detect the variant though testing arrivals at UK borders, hospital admissions, and the general community. We found that sampling 10- 50% of arrivals at UK borders could confer a speed advantage of 3.5-6 weeks over existing community surveillance, and 1.5–5 weeks (depending on IHR) over hospital testing. We conclude that directing limited global capacity for surveillance to highly connected ports could speed up global detection of novel SARS-CoV-2 variants.
bioRxiv
10-04-2023
Preimpreso
Público en general
VIRUS RESPIRATORIOS
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