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Optimal, near-optimal, and robust epidemic control
Dylan H. Morris.
Fernando W. Rossine.
Joshua B. Plotkin.
Simon A. Levin.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://arxiv.org/pdf/2004.02209v1.pdf
The COVID-19 pandemic has highlighted the need for control measures that reduce the epidemic peak ("flattening the curve"). Here we derive the optimal time-limited intervention for reducing peak epidemic prevalence in the standard Susceptible-Infectious-Recovered (SIR) model. We show that alternative, more practical interventions can perform nearly as well as the provably optimal strategy. However, none of these strategies are robust to implementation errors: mistiming the start of the intervention by even a single week can be enormously costly, for realistic epidemic parameters. Sustained control measures, though less efficient than optimal and near-optimal time-limited interventions, can be used in combination with time-limited strategies to mitigate the catastrophic risks of mistiming.
arxiv.org
2020
Artículo
https://arxiv.org/pdf/2004.02209v1.pdf
Inglés
VIRUS RESPIRATORIOS
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