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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/982| A potential role for integrins in host cell entry by SARS-CoV-2 | |
| Sigrist, C Bridge, A Le Mercier, P | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| Highlights • Integrin may act as an alternative receptor for SARS-CoV-2 and could be implicated in its transmission and pathology. • The spike protein of SARS-CoV-2 acquired a RGD motif known to bind integrins. This motif is absent from other coronaviruses. • The integrin-binding motif is present at the surface of the spike protein, close to the ACE2 receptor-binding region. • Integrin binding may be a promising therapeutics target, and should be tested experimentally. | |
| Antiviral Research | |
| 2020 | |
| Preimpreso | |
| https://coronavirus.1science.com/item/d925c45ef2ee739184d1c0b5c56ed505d2cd3e0e | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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| Fichero | Tamaño | Formato | |
|---|---|---|---|
| 104231.pdf | 2.51 MB | Adobe PDF | Visualizar/Abrir |