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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/898
Identification Sus scrofa and Mus musculus as potential hosts of SARS-CoV-2 via phylogenetic and homologous recombination analysis | |
Hu, X Li, W He, Z Zhang, F | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
Background: Wuhan Huanan seafood wholesale market is highly suspected as the original place for the outbreak of SARS-CoV-2 previously. Most studies focus on the livestock being sold in the market, neglecting that the livestock living around the city of Wuhan could also be the original hosts. Methods: First, relative synonymous codon usage was utilized to analyze the potential hosts of SARS-CoV-2; Then cluster SARS-CoV-2 and related coronavirus through the phylogenetic tree. Next, we used Recombination Detection Program to identify the possible recombination region, as well as verifying via Simplot. Results: Related coronavirus from porcine or murine sources may faciliatate the evolution and reorganization of SARS-CoV-2. Conclusions: Overall, to our knowledge, this is the first paper to illustrate that swine and mice could be probable reservoirs for the SARS-CoV-2. | |
F1000Research | |
2020 | |
Preimpreso | |
https://coronavirus.1science.com/item/0868f0e986ebda7c1ad02ebd23ab9f5d2e3681e8 | |
Inglés | |
VIRUS RESPIRATORIOS | |
Aparece en las colecciones: | Artículos científicos |
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