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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/878| Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells | |
| Matsuyama, S Nao, N Shirato, K Kawase, M Saito, S Takayama, I Nagata, N Sekizuka, T Katoh, H Kato, F Sakata, M Tahara, M Kutsuna, S Ohmagari, N Kuroda, M Suzuki, T Kageyama, T Takeda, M | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused a large respiratory outbreak in Wuhan, China in December 2019, is currently spreading across many countries globally. Here, we show that a TMPRSS2-expressing VeroE6 cell line is highly susceptible to SARS-CoV-2 infection, making it useful for isolating and propagating SARS-CoV-2. Our results reveal that, in common with SARS- and Middle East respiratory syndrome-CoV, SARS-CoV-2 infection is enhanced by TMPRSS2. | |
| Proceedings of the National Academy of Sciences of the United States of America | |
| 2020 | |
| Preimpreso | |
| https://coronavirus.1science.com/item/2f3431c06da8e9dc5d1e73df48fe0cabcfccde5b | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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