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Molecular Detection and Characterization of Porcine Epidemic Diarrhea Virus and Porcine Aichivirus C Coinfection in México
LUIS LOZANO AGUIRRE BELTRÁN
MARIA ELENA TRUJILLO ORTEGA
SOFIA LIZETH ALCARAZ-ESTRADA
Montserrat Elemi García Hernández
Carlos Sandoval-Jaime
Blanca Taboada
Rosa Elena Sarmiento-Silva
Acceso Abierto
Atribución
https://doi.org/10.3390/v13050738
Swine enteric viral infections are responsible for substantial economic losses in the pork in- dustry worldwide. Porcine epidemic diarrhea (PEDV) is one of the main causative agents of diarrhea in lactating pigs, and reports of PEDV coinfection with other enteric viruses highlight the importance of viral interactions for disease presentation and outcomes. Using next-generation sequencing (NGS) and sequence analyses from samples taken from piglets with acute diarrhea, we explored the possible interactions between PEDV and other less reported pathogens. PEDV coinfection with porcine kobuvirus (PKV) was detected in 36.4% (27/74) of samples. Full genomes from porcine coronavirus and kobuvirus were obtained, as was a partial porcine sapovirus genome (PSaV). The phylogenetic results show the clustering of these strains corresponding to the geographical relationship. To our knowledge, this is the first full genome and isolation report for porcine kobuvirus in México, as well as the first phylogenetic analysis for porcine sapovirus in the country. The NGS approach provides a better perspective of circulating viruses and other pathogens in affected production units.
Viruses
23-04-2021
Artículo
https://www.mdpi.com/
Inglés
García-Hernández, M.-E.; Trujillo-Ortega, M.-E.; Alcaraz-Estrada, S.-L.; Lozano-Aguirre-Beltrán, L.; Sandoval-Jaime, C.; Taboada-Ramírez, B.I.; Sarmiento-Silva, R.-E. Molecular Detection and Characterization of Porcine Epidemic Diarrhea Virus and Porcine Aichivirus C Coinfection in México. Viruses 2021, 13, 738. https://doi.org/10.3390/v13050738
VIRUS RESPIRATORIOS
Versión publicada
publishedVersion - Versión publicada
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