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Dominance of three sublineages of the SARS-CoV-2 Delta variant in Mexico | |
Blanca Taboada CLAUDIA SELENE ZARATE GUERRA RODRIGO GARCIA LOPEZ JOSE ESTEBAN MUÑOZ MEDINA Alfredo Herrera_Estrella Celia Boukadida Bruno Gómez Gil Rodríguez Sala NELLY SELEM MOJICA MAURICIO ROSALES RIVERA ANGEL GUSTAVO SALAS LAIS ROSA MARIA GUTIERREZ RIOS JOSE ANTONIO LOZA ROMAN XAIRA JIMENA RIVERA GUTIERREZ JOEL ARMANDO VAZQUEZ PEREZ Margarita Matías Florentino MARISSA PEREZ GARCIA SANTIAGO AVILA RIOS JUAN MANUEL HURTADO CERVANTES Carla Herrera-Najera JOSÉ NÚÑEZ CONTRERAS BRENDA SARQUIZ MARTINEZ VÍCTOR GARCÍA ARIAS BERNARDO MARTINEZ MIGUEL CRISTOBAL CHAIDEZ QUIROZ PAVEL ISA ROSA MARIA WONG CHEW MARIA EUGENIA JIMENEZ CORONA SUSANA LOPEZ CHARRETON CARLOS FEDERICO ARIAS ORTIZ | |
Acceso Abierto | |
Atribución-NoComercial | |
doi: 10.20944/preprints202205.0131.v1 | |
In this study, we analyzed sequences of SARS-CoV-2 isolates of the Delta variant in Mexico, which completely replaced other previously circulating variants in the country due to its transmission advantage. Among Delta sublineages detected, 81.5 % were classified as AY.20, AY.26, and AY.100. According to publicly available data, these sublineages only reached a world prevalence of less than 1%, suggesting a possible Mexican origin. The signature mutations of these sublineages are described, and phylogenetic analyses and haplotype networks were used to track their spread across the country. Other frequently detected sublineages include AY.3, AY.62, AY.103, and AY.113. Over time, the principal sublineages showed different geographical distributions, with AY.20 predominant in Central Mexico, AY.26 in the North, and AY.100 in the Northwest and South/Southeast. This work describes the circulation, from May to November 2021, of the primary sublineages of the Delta variants associated to the third wave of the COVID-19 pandemic in Mexico and reinforces the importance of SARS-CoV-2 genomic surveillance for timely identification of emerging variants that may impact public health. | |
10-05-2022 | |
Preimpreso | |
https://www.preprints.org/ | |
Inglés | |
Taboada, B.; Zárate, S.; García-López, R.; Muñoz-Medina, J.E.; Sanchez-Flores, A.; Herrera-Estrella, A.; Boukadida, C.; Gómez-Gil, B.; Mojica, N.S.; Rosales-Rivera, M.; Salas-Lais, A.G.; Gutiérrez-Ríos, R.M.; Loza, A.; Rivera-Gutierrez, X.; Vazquez-Perez, J.A.; Matías-Florentino, M.; Pérez-García, M.; Ávila-Ríos, S.; Hurtado, J.M.; Herrera-Nájera, C.I.; Núñez-Contreras, J.J.; Sarquiz-Martínez, B.; García-Arias, V.E.; Santiago-Mauricio, M.G.; Martínez-Miguel, B.; Enciso-Ibarra, J.; Cháidez-Quiróz, C.; Iša, P.; Wong-Chew, R.M.; Jiménez-Corona, M.-E.; López, S.; Arias, C.F. Dominance of Three Sub | |
VIRUS RESPIRATORIOS | |
Borrador | |
draft - Borrador | |
Aparece en las colecciones: | Artículos científicos |
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