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Dominance of three sublineages of the SARS-CoV-2 Delta variant in Mexico
Blanca Taboada
CLAUDIA SELENE ZARATE GUERRA
RODRIGO GARCIA LOPEZ
JOSE ESTEBAN MUÑOZ MEDINA
Alfredo Herrera_Estrella
Celia Boukadida
Bruno Gómez Gil Rodríguez Sala
NELLY SELEM MOJICA
MAURICIO ROSALES RIVERA
ANGEL GUSTAVO SALAS LAIS
ROSA MARIA GUTIERREZ RIOS
JOSE ANTONIO LOZA ROMAN
XAIRA JIMENA RIVERA GUTIERREZ
JOEL ARMANDO VAZQUEZ PEREZ
Margarita Matías Florentino
MARISSA PEREZ GARCIA
SANTIAGO AVILA RIOS
JUAN MANUEL HURTADO CERVANTES
Carla Herrera-Najera
JOSÉ NÚÑEZ CONTRERAS
BRENDA SARQUIZ MARTINEZ
VÍCTOR GARCÍA ARIAS
BERNARDO MARTINEZ MIGUEL
CRISTOBAL CHAIDEZ QUIROZ
PAVEL ISA
ROSA MARIA WONG CHEW
MARIA EUGENIA JIMENEZ CORONA
SUSANA LOPEZ CHARRETON
CARLOS FEDERICO ARIAS ORTIZ
Acceso Abierto
Atribución-NoComercial
doi: 10.20944/preprints202205.0131.v1
In this study, we analyzed sequences of SARS-CoV-2 isolates of the Delta variant in Mexico, which completely replaced other previously circulating variants in the country due to its transmission advantage. Among Delta sublineages detected, 81.5 % were classified as AY.20, AY.26, and AY.100. According to publicly available data, these sublineages only reached a world prevalence of less than 1%, suggesting a possible Mexican origin. The signature mutations of these sublineages are described, and phylogenetic analyses and haplotype networks were used to track their spread across the country. Other frequently detected sublineages include AY.3, AY.62, AY.103, and AY.113. Over time, the principal sublineages showed different geographical distributions, with AY.20 predominant in Central Mexico, AY.26 in the North, and AY.100 in the Northwest and South/Southeast. This work describes the circulation, from May to November 2021, of the primary sublineages of the Delta variants associated to the third wave of the COVID-19 pandemic in Mexico and reinforces the importance of SARS-CoV-2 genomic surveillance for timely identification of emerging variants that may impact public health.
10-05-2022
Preimpreso
https://www.preprints.org/
Inglés
Taboada, B.; Zárate, S.; García-López, R.; Muñoz-Medina, J.E.; Sanchez-Flores, A.; Herrera-Estrella, A.; Boukadida, C.; Gómez-Gil, B.; Mojica, N.S.; Rosales-Rivera, M.; Salas-Lais, A.G.; Gutiérrez-Ríos, R.M.; Loza, A.; Rivera-Gutierrez, X.; Vazquez-Perez, J.A.; Matías-Florentino, M.; Pérez-García, M.; Ávila-Ríos, S.; Hurtado, J.M.; Herrera-Nájera, C.I.; Núñez-Contreras, J.J.; Sarquiz-Martínez, B.; García-Arias, V.E.; Santiago-Mauricio, M.G.; Martínez-Miguel, B.; Enciso-Ibarra, J.; Cháidez-Quiróz, C.; Iša, P.; Wong-Chew, R.M.; Jiménez-Corona, M.-E.; López, S.; Arias, C.F. Dominance of Three Sub
VIRUS RESPIRATORIOS
Borrador
draft - Borrador
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