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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/7871| Estimation of COVID-19 cases in Mexico accounting for SARS-CoV-2 RT-PCR false negative results | |
| ISAAC NÚÑEZ PABLO FRANCISCO BELAUNZARAN ZAMUDIO YANINK NERIED CARO VEGA | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| https://doi.org/10.1101/2020.09.17.20197038 | |
| nderestimation of the number of cases during the COVID-19 pandemic has been a constant concern worldwide. Case confirmation is based on identification of SARS-CoV-2 RNA using real time polymerase chain reaction (RT-PCR) in clinical samples. However, these tests have suboptimal sensitivity, especially during the early and late course of infection. Using open data, we estimated that among 1 343 730 people tested in Mexico since February 27th, there were 838 377 (95% CL 734 605 – 1 057 164) cases, compared with 604 376 considering only positive tests. ICU admissions and deaths were around 16% and 9% higher than reported. Thus, we show that accounting for the sensitivity of SARS-Cov-2 RT-PCR diagnostic tests is a simple way to improve estimations for the true number of COVID-19 cases in tested people, particularly in high-prevalence populations. This could aid to better inform public health measures and reopening policies. | |
| Medrxiv | |
| 21-09-2020 | |
| Preimpreso | |
| medrxiv.org/ | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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| Estimation of COVID-19 cases in Mexico accounting for SARS-CoV-2 RT-PCR false negative results.pdf | 244.81 kB | Adobe PDF | Visualizar/Abrir |