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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/7660| The course of COVID-19 in patients with chronic spontaneous urticaria receiving omalizumab treatment | |
| EMEL ATAYIK Gökhan Aytekin | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| https://doi.org/10.1101/2022.01.29.22270077 | |
| https://www.medrxiv.org/content/10.1101/2022.01.29.22270077v1 | |
| Introduction: Although there are case reports and guideline recommendations that states omalizumab can be used in chronic spontaneous urticaria (CSU) patients during the SARS-CoV-2 pandemic, there are scarce studies showing the course of Coronavirus disease 2019 (COVID-19) in CSU patients receiving omalizumab. Materials and Methods: A total of 370 patients with chronic urticaria were included in the study between June 2020 and December 31, 2020. Results: Sixty patients (16.2%) became infected with the SARS-CoV-2. The rate of pneumonia and hospitalization were 4.1% and 1.9%. There was no significant difference was determined between the CSU patients with omalizumab treatment and the non-receivers in regard to the rate of SARS-CoV-2 (+) (p: 0.567) and in regard to the rate of SARS-CoV-2 related pneumonia and hospitalization (p: 0.331 and p: 0.690). Gender, duration of CSU, serum IgE levels, omalizumab treatment, and atopy were not found to be associated with an increased risk for SARS-CoV-2 positivity in patients with CSU. Conclusion: Our study shows that the use of omalizumab does not increase the risk of COVID-19 infection, COVID-19-related pneumonia, and hospitalizations in CSU patients and supports the view that omalizumab can be used safely in patients with CSU during the COVID-19 pandemic. Keywords: chronic spontaneous urticaria, omalizumab, COVID-19 | |
| medRxiv and bioRxiv | |
| 01-02-2022 | |
| Preimpreso | |
| https://www.medrxiv.org/ | |
| Inglés | |
| Epidemia COVID-19 | |
| Público en general | |
| VIRUS RESPIRATORIOS | |
| Versión publicada | |
| publishedVersion - Versión publicada | |
| Aparece en las colecciones: | Artículos científicos |
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