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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/7636| Detection of SARS-CoV-2 Omicron, Delta, Alpha and Gamma variants using a rapid antigen test | |
| Nol Salcedo Nidhi Nandu Julie Boucau Bobby Brooke Herrera | |
| Acceso Abierto | |
| Atribución-SinDerivadas | |
| https://doi.org/10.1101/2022.01.27.22269299 | |
| https://www.medrxiv.org/content/10.1101/2022.01.27.22269299v1 | |
| Throughout the coronavirus disease 2019 (COVID-19) pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have emerged with different infection and disease dynamics. Testing strategies, including clinical diagnosis, surveillance, and screening, have been deployed to help limit the spread of SARS-CoV-2 variants. Rapid antigen tests, in particular, have been approved for self-testing in many countries and governments are supporting their manufacturing and distribution. However, studies demonstrating the accuracy of rapid antigen tests in detecting SARS-CoV-2 variants, especially the new Omicron variant, are limited. We determined the analytical sensitivity of a CE-marked rapid antigen test against the Omicron, Delta, Alpha and Gamma variants. The rapid antigen test had the most sensitive limit of detection (10 plaque forming units [PFU]/mL) when tested with the Alpha and Gamma variants, followed by the Omicron (100 PFU/mL) and Delta (1,000 PFU/mL) variants. Given the increasing numbers of breakthrough infections and the need to surveil infectiousness, rapid antigen tests are effective public health tools to detect SARS-CoV-2 variants. | |
| medRxiv and bioRxiv | |
| 28-01-2022 | |
| Preimpreso | |
| https://www.medrxiv.org | |
| Inglés | |
| Epidemia COVID-19 | |
| Público en general | |
| VIRUS RESPIRATORIOS | |
| Versión publicada | |
| publishedVersion - Versión publicada | |
| Aparece en las colecciones: | Artículos científicos |
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| Detection of SARS COV2 Omicron, Delta, Alpha and Gamma.pdf | 1.21 MB | Adobe PDF | Visualizar/Abrir |