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High prevalence of olfactory disorders 18 months after contracting COVID-19 | |
Arnaud Tognetti Evelina Thunell Mats J Olsson Nina Greilert Norin Sebastian Havervall Charlotte Thålin Johan Lundström | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
https://doi.org/10.1101/2022.01.20.22269490 | |
https://www.medrxiv.org/content/10.1101/2022.01.20.22269490v1 | |
Reduced olfactory function is the symptom with the highest prevalence in COVID-19 with nearly 70% of individuals with COVID-19 experiencing partial or total loss of their sense of smell at some point during the disease. Recent reports suggest that more than 7 months after recovering from COVID-19, a large proportion of these individuals still have olfactory dysfunction of some form. To establish the prevalence of olfactory dysfunction 18 months and beyond, we tested 100 individuals with established COVID-19 in the first wave of the pandemic using psychophysical full-scale testing of smell and taste functions as well as assessments of parosmia. Participants were recruited from an ongoing study, comprising healthcare workers at a hospital in Stockholm, Sweden, that are regularly tested for SARS-CoV-2 IgG antibodies since the start of the pandemic in Sweden. To assess potential skewed recruitment of individuals with prior olfactory dysfunction and assess normal rate of dysfunctions in the used population, 44 SARS-CoV-2 IgG naive individuals were also tested as a control group. One and a half year after COVID-19, more than one third of individuals recovered from COVID-19 demonstrated a clinical reduction in their sense of smell. Critically, nearly half of COVID-19-recovered individuals complaint about parosmia. Prevalence of gustatory dysfunction was, however, low (3%). In summary, a full 65% of individuals recovered from COVID-19 experience olfactory dysfunction of some form 18 months later. Given the amount of time since initial insult to the olfactory system, it is likely that these olfactory problems are permanent. | |
medRxiv and bioRxiv | |
20-01-2022 | |
Preimpreso | |
www.medrxiv.org | |
Inglés | |
Epidemia COVID-19 | |
Público en general | |
VIRUS RESPIRATORIOS | |
Versión publicada | |
publishedVersion - Versión publicada | |
Aparece en las colecciones: | Artículos científicos |
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