Please use this identifier to cite or link to this item: https://covid-19.conacyt.mx/jspui/handle/1000/754
Prolonged Viral Shedding in Feces of Pediatric Patients with Coronavirus Disease 2019
Xing, Y
Ni, W
Wu, Q
Li, W
Li, G
Wang, W
Tong, J
Song, X
Wing-Kin Wong, G
Xing, Q
Acceso Abierto
Atribución-NoComercial-SinDerivadas
Objective To determine the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory and fecal specimens in children with coronavirus disease 2019 (COVID-19). Methods From January 17, 2020 to February 23, 2020, three paediatric cases of COVID-19 were reported in Qingdao, Shandong Province, China. Epidemiological, clinical, laboratory, and radiological characteristics and treatment data were collected. Patients were followed up to March 10, 2020, and dynamic profiles of nucleic acid testing results in throat swabs and fecal specimens were closely monitored. Results Clearance of SARS-CoV-2 in respiratory tract occurred within two weeks after abatement of fever, whereas viral RNA remained detectable in stools of pediatric patients for longer than 4 weeks. Two children had fecal SARS-CoV-2 undetectable 20 days after throat swabs showing negative, while that of another child lagged behind for 8 days. Conclusions SARS-CoV-2 may exist in children’s gastrointestinal tract for a longer time than respiratory system. Persistent shedding of SARS-CoV-2 in stools of infected children raises the possibility that the virus might be transmitted through contaminated fomites. Massive efforts should be made at all levels to prevent spreading of the infection among children after reopening of kindergartens and schools.
Journal of Microbiology, Immunology, and Infection / Wei Mian Yu Gan Ran za Zhi
2020
Preimpreso
https://coronavirus.1science.com/item/4bd3f16403c9c1d2f7668f18722d321c44d19c09
Inglés
VIRUS RESPIRATORIOS
Appears in Collections:Artículos científicos

Upload archives


File SizeFormat 
101941.pdf1.16 MBAdobe PDFView/Open