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SARS-CoV-2 T cell responses are expected to remain robust against Omicron
Syed Faraz Ahmed
Ahmed Abdul Quadeer
Matthew McKay
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://doi.org/10.1101/2021.12.12.472315
https://www.biorxiv.org/content/10.1101/2021.12.12.472315v1.article-info
Omicron, the most recent SARS-CoV-2 variant of concern (VOC), harbours multiple mutations in the spike protein that were not observed in previous VOCs. Initial studies suggest Omicron to substantially reduce the neutralizing capability of antibodies induced from vaccines and previous infection. However, its effect on T cell responses remains to be determined. Here, we assess the effect of Omicron mutations on known T cell epitopes and report data suggesting T cell responses to remain broadly robust against this new variant.
medRxiv and bioRxiv
12-12-2021
Preimpreso
https://www.biorxiv.org/content/10.1101/2021.12.12.472315v1
Inglés
Epidemia COVID-19
Investigadores
Público en general
VIRUS RESPIRATORIOS
Versión publicada
publishedVersion - Versión publicada
Aparece en las colecciones: Artículos científicos

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