Please use this identifier to cite or link to this item: https://covid-19.conacyt.mx/jspui/handle/1000/7266
SARS-CoV-2 infection: Understanding the immune system abnormalities to get an adequate diagnosis
Karen Medina-Quero
Omar Barreto Rodríguez
Voltaire Méndez
Anahí Sánchez-Monciváis
IVETTE BUENDIA ROLDAN
LESLIE CHAVEZ GALAN
Acceso Abierto
Atribución-NoComercial
https://doi.org/10.17305/bjbms.2020.5400
https://www.bjbms.org/ojs/index.php/bjbms/article/view/5400
COVID-19 is the current pandemic caused by the novel coronavirus, SARS-CoV-2, that emerged from China at the end of December 2019. The scientific community is making extraordinary efforts to understand the virus structure and the pathophysiology and immunological processes activated in the host, in order to identify biomarkers, diagnostic tools, treatments, and vaccines to decrease COVID-19 incidence and mortality. Various abnormalities have been noted during SARS-CoV-2 infection both in lymphoid and myeloid cells. Such abnormalities may disturb the immune system function and cause a massive inflammatory response that impairs tissue function. This review discusses the close relationship between the immune system abnormalities and the broad spectrum of clinical manifestations, including fibrosis, in the context of COVID-19 disease. Moreover, we described the current strategies for COVID-19 diagnosis, and we provide a summary of the most useful clinical laboratory parameters to identify severe COVID-19 patients.
BJBMS
13-02-2021
Artículo
www.bjbms.org
Inglés
Epidemia COVID-19
Público en general
Medina-Quero K, Barreto-Rodriguez O, Mendez-Rodriguez V, Sanchez-Moncivais A, Buendia-Roldan I, Chavez-Galan L. SARS-CoV-2 infection: Understanding the immune system abnormalities to get an adequate diagnosis. Bosn J of Basic Med Sci [Internet]. 2021Feb.13 [cited 2021Jul.16];. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/5400
VIRUS RESPIRATORIOS
Versión publicada
publishedVersion - Versión publicada
Appears in Collections:Artículos científicos

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