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Emergence and spread of the potential variant of interest (VOI) B.1.1.519 predominantly present in Mexico
Abril Rodriguez-Maldonado
Joel Vazquez-Perez
Alberto Cedro-Tanda
Blanca Taboada
Celia Boukadida
Tatiana Ernestina Nuñez García
Natividad Cruz Ortiz
Gisela Barrera
Lucía Hernández-Rivas
IRMA LOPEZ MARTINEZ
Alfredo Mendoza-Vargas
Juan Pablo Reyes
Nicolas Alcaraz
Fernando Penaloza
Dulibeth González Barrera
Daniel Rangel De Leon
Luis A. Herrera
FIDENCIO MEJIA NEPOMUCENO
ALEJANDRA HERNANDEZ TERAN
Mario Mújica Sánchez
EDUARDO BECERRIL
Jose arturo Martinez orozco
Rogelio Perez-Padilla
JORGE SALAS HERNANDEZ
Alejandro Sanchez_Flores
Pavel Isa
Margarita Matías Florentino
SANTIAGO AVILA RIOS
José Esteban Muñoz Medina
Concepción Grajales Muñiz
Angel Gustavo Salas Lais
Andrea Santos Coy_Arechavaleta
Alfredo Hidalgo_Miranda
Carlos Arias
JOSE ERNESTO RAMIREZ-GONZALEZ
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://doi.org/10.1101/2021.05.18.21255620
https://www.medrxiv.org/content/10.1101/2021.05.18.21255620v1
SARS-CoV-2 variants have emerged in late 2020 and there are at least three variants of concern (B.1.1.7, B.1.351, P1) reported by WHO. These variants have several substitutions in the Spike protein that affect receptor binding; they present increased transmissibility and may be associated with reduced vaccine effectiveness. In the present work, we are reporting the identification of a potential variant of interest harboring the mutations T478K, P681H, and T732A in the Spike protein, within the newly named lineage B.1.1.519, which rapidly outcompeted the preexisting variants in Mexico and has been the dominant virus in the country during the first trimester of 2021.
medRxiv and bioRxiv
20-05-2021
Preimpreso
https://www.medrxiv.org
Inglés
Epidemia COVID-19
Público en general
VIRUS RESPIRATORIOS
Versión publicada
publishedVersion - Versión publicada
Aparece en las colecciones: Artículos científicos

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