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Emergence and spread of the potential variant of interest (VOI) B.1.1.519 predominantly present in Mexico | |
Abril Rodriguez-Maldonado Joel Vazquez-Perez Alberto Cedro-Tanda Blanca Taboada Celia Boukadida Tatiana Ernestina Nuñez García Natividad Cruz Ortiz Gisela Barrera Lucía Hernández-Rivas IRMA LOPEZ MARTINEZ Alfredo Mendoza-Vargas Juan Pablo Reyes Nicolas Alcaraz Fernando Penaloza Dulibeth González Barrera Daniel Rangel De Leon Luis A. Herrera FIDENCIO MEJIA NEPOMUCENO ALEJANDRA HERNANDEZ TERAN Mario Mújica Sánchez EDUARDO BECERRIL Jose arturo Martinez orozco Rogelio Perez-Padilla JORGE SALAS HERNANDEZ Alejandro Sanchez_Flores Pavel Isa Margarita Matías Florentino SANTIAGO AVILA RIOS José Esteban Muñoz Medina Concepción Grajales Muñiz Angel Gustavo Salas Lais Andrea Santos Coy_Arechavaleta Alfredo Hidalgo_Miranda Carlos Arias JOSE ERNESTO RAMIREZ-GONZALEZ | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
https://doi.org/10.1101/2021.05.18.21255620 | |
https://www.medrxiv.org/content/10.1101/2021.05.18.21255620v1 | |
SARS-CoV-2 variants have emerged in late 2020 and there are at least three variants of concern (B.1.1.7, B.1.351, P1) reported by WHO. These variants have several substitutions in the Spike protein that affect receptor binding; they present increased transmissibility and may be associated with reduced vaccine effectiveness. In the present work, we are reporting the identification of a potential variant of interest harboring the mutations T478K, P681H, and T732A in the Spike protein, within the newly named lineage B.1.1.519, which rapidly outcompeted the preexisting variants in Mexico and has been the dominant virus in the country during the first trimester of 2021. | |
medRxiv and bioRxiv | |
20-05-2021 | |
Preimpreso | |
https://www.medrxiv.org | |
Inglés | |
Epidemia COVID-19 | |
Público en general | |
VIRUS RESPIRATORIOS | |
Versión publicada | |
publishedVersion - Versión publicada | |
Appears in Collections: | Artículos científicos |
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