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Serological prevalence of SARS-CoV-2 infection and associated factors in health care workers in a “non-COVID” hospital in Mexico City | |
ESTEBAN CRUZ ARENAS ELIZABETH CABRERA RUIZ Sara Laguna Barcenas CLAUDIA ADRIANA COLIN CASTRO Tatiana Chávez RAFAEL FRANCO CENDEJAS José Clemente Ibarra Ponce de León JAVIER PEREZ ORIVE | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
https://doi.org/10.1101/2020.11.30.20241331 | |
https://www.medrxiv.org/content/10.1101/2020.11.30.20241331v1 | |
Background Mexico is one of the countries with the highest number of deaths from the COVID-19 pandemic. However, the number of confirmed cases and RT-PCR tests per million population are lower than for other countries, which leads to uncertainty about the actual extent of the pandemic. In Mexico City, health care workers represent an important fraction of individuals with SARS-CoV-2 infection. This work aims to estimate the frequency of antibodies to SARS-CoV-2 in health care workers at a non-COVID hospital, as well as identify factors associated with SARS-CoV-2 infection in this population. Methods We conducted a serological survey in a large non-COVID teaching hospital in Mexico City. The study population included all the personnel that works, in any capacity, in the hospital. From this population we selected a representative sample of 300 individuals. Blood samples were collected and questionnaires were applied between August 10th and September 9th, 2020. Results ELISA results indicate a serological prevalence to SARS-CoV-2 infection of 13.0%. Working in the janitorial and security groups, having an educational level below a university degree, and living with larger numbers of people, were also identified as sociodemographic factors that increase the risk of having SARS-CoV-2 infection. Conclusions Even though the rate from the official number of confirmed cases in Mexico City is substantially smaller than the seropositive rate identified in this work, even in health care workers there is still a majority of individuals that are seronegative, and thus the risk of continued epidemic waves and mortality remains high. | |
medRxiv and bioRxiv | |
02-12-2020 | |
Preimpreso | |
www.medrxiv.org | |
Inglés | |
Epidemia COVID-19 | |
Público en general | |
VIRUS RESPIRATORIOS | |
Versión publicada | |
publishedVersion - Versión publicada | |
Aparece en las colecciones: | Artículos científicos |
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