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A computational analysis on Covid-19 transmission raises imuuno-epidemiology concerns.
anthony Kyriakopoulos
Shi Zhao
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://doi.org/10.1101/2020.11.11.20229641
For Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) the investigation of the heterogeneity of individual infectiousness becomes important due to the cross reactive immunity of general population. Using a sample of infected population with SARS-COV-2 in close geographical proximity to the initial Severe Advanced Respiratory Syndrome-1 [SARS-1] outbreak, we explored the association between infectors age and dispersion (or heterogeneity) of individual infectiousness (k) in order to investigate the relatedness with the age of an individuals capability to disperse SARS-COV-2. Interestingly, we find a negative association between k and increase of infectors age. Significantly this becomes more evident for the age group of 20-60 years comparing with the infectors with younger age. This raises important immuno-epidemiology concerns for effectiveness of public health measures to contain the disease.
medRxiv and bioRxiv
13-11-2020
Documento de trabajo
www.medrxiv.org
Inglés
Epidemia COVID-19
Público en general
VIRUS RESPIRATORIOS
Versión publicada
publishedVersion - Versión publicada
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