Please use this identifier to cite or link to this item: https://covid-19.conacyt.mx/jspui/handle/1000/642
COVID-19 infection: origin, transmission, and characteristics of human coronaviruses
Adnan Shereen, M
Khan, S
Kazmi, A
Bashir, N
Siddique, R
Acceso Abierto
Atribución-NoComercial-SinDerivadas
The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China and spread around the world. Genomic analysis revealed that SARS-CoV-2 is phylogenetically related to severe acute respiratory syndrome-like (SARS-like) bat viruses, therefore bats could be the possible primary reservoir. The intermediate source of origin and transfer to humans is not known, however, the rapid human to human transfer has been confirmed widely. There is no clinically approved antiviral drug or vaccine available to be used against COVID-19. However, few broad-spectrum antiviral drugs have been evaluated against COVID-19 in clinical trials, resulted in clinical recovery. In the current review, we summarize and comparatively analyze the emergence and pathogenicity of COVID-19 infection and previous human coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and middle east respiratory syndrome coronavirus (MERS-CoV). We also discuss the approaches for developing effective vaccines and therapeutic combinations to cope with this viral outbreak.
Journal of Advanced Research
2020
Preimpreso
https://coronavirus.1science.com/item/8e59b2566ff858dd6ed97a86abe1741acf0de4a6
Inglés
VIRUS RESPIRATORIOS
Appears in Collections:Artículos científicos

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