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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/617| Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants | |
| ul Qamar, M Alqahtani, S Alamri, M Chen, L | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| Highlights • SARS-CoV-2 3CL pro is conserved, share 99.02% sequence identity with SARS-CoV 3CL pro and together with 12 point-mutations. • Mutations disrupt important hydrogen bonds and alter the receptor binding site of SARS-CoV-2 3CL pro . • Medicinal plants phytochemicals were proved potential anti-COVID-19 druggable candidates. | |
| Journal of Pharmaceutical Analysis | |
| 2020 | |
| Preimpreso | |
| https://coronavirus.1science.com/item/aac93c166fe3b9058b9d7ea387c1fa18d3fbb0d0 | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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|---|---|---|---|
| 100511.pdf | 3.21 MB | Adobe PDF | Visualizar/Abrir |