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Descriptive study of the first 63 cases of the ongoing SARS-CoV-2 outbreak at the transportation hub city Xuzhou in China
Wang Liang.
Yan Jiawei.
Liu Zhanzhong.
Yang Jianye.
Du Yangguang.
Wise Michael.
Wu Mingqiu.
Xi Xiangyu.
Zhang Xiao.
Gu Bing.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.21203/rs.3.rs-21379/v1
A novel coronavirus (SARS-CoV-2) outbreak from Wuhan, China has, as of February 13, 2020, infected nearly 60,000 people in China with the death toll passing 1300. The virus is also spreading worldwide rapidly, with 490 confirmed cases in 24 countries and 1 death at current stage. Numerous studies have recently been published in terms of genome structure, transmission, infection mechanism, and drug development of the SARS-CoV-2 virus. In this study, we performed a descriptive study by focusing on the first 63 confirmed COVID-19 cases in Xuzhou, a major city and a transportation hub with 10.44 million population (National Bureau of Statistics of China, 2019) on the east coast of China. Among the 63 patients with confirmed COVID-19, the median age is 45-year-old and 49.21% are male. 23 cases (36.51%) are imported. 23 cases (36.51%) were confirmed between from January 26 to 31 while 40 cases (63.49%) from February 1 to 10. The mean period from isolation to confirmation is 4.95 days. Among the ten administrative divisions of Xuzhou city, Suining county (n=17) and Pizhou City (n=15) have the most cases while Tongshan district has none. A representative familial cluster was analysed in detail in order to get a better understanding of the transmission routes of the virus. Clinical symptoms associated with COVID-19 in 41 confirmed cases were analysed, which could provide a meaningful understanding during the initial screening of the disease. In sum, this study provides an epidemiological overview of the SARS-CoV-2 outbreak in Xuzhou, the economic hub of Huaihai Economic Zone (HEZ) and an important transportation center in China. Considering the ongoing situation of this newly emerged infection both domestically and internationally, more efforts should be required to reduce the transmission of the virus so as to avoid further casualties, economic losses, and global pandemic.Authors Liang Wang, Jiawei Yan, and Zhanzhong Liu contributed equally to this study.
assets.researchsquare.com
2020
Artículo
https://assets.researchsquare.com/files/rs-21379/v1/manuscript.pdf
Inglés
VIRUS RESPIRATORIOS
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