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Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer
Tian, S
Hu, W
Niu, L
Liu, H
Xu, H
Xiao, S
Acceso Abierto
Atribución-NoComercial-SinDerivadas
There is currently a lack of pathologic data on the novel coronavirus (severe acute respiratory syndrome coronavirus 2) pneumonia, or coronavirus disease 2019 (COVID-19), from autopsy or biopsy. Two patients who recently underwent lung lobectomies for adenocarcinoma were retrospectively found to have had COVID-19 at the time of the operation. These two cases thus provide important first opportunities to study the pathology of COVID-19. Pathologic examinations revealed that apart from the tumors, the lungs of both patients exhibited edema, proteinaceous exudate, focal reactive hyperplasia of pneumocytes with patchy inflammatory cellular infiltration, and multinucleated giant cells. Hyaline membranes were not prominent. Because both patients did not exhibit symptoms of pneumonia at the time of operation, these changes likely represent an early phase of the lung pathology of COVID-19 pneumonia.
Journal of Thoracic Oncology
2020
Preimpreso
https://coronavirus.1science.com/item/f3f6f82ea7d94594726eed34da9103ba9fbb34a3
Inglés
VIRUS RESPIRATORIOS
Aparece en las colecciones: Artículos científicos

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