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Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures
Pung Rachael.
Chiew Calvin J.
Young Barnaby E.
Chin Sarah.
Chen Mark I-C.
Clapham Hannah E.
Cook Alex R.
Maurer-Stroh Sebastian.
Toh Matthias P H S.
Poh Cuiqin.
Low Mabel.
Lum Joshua.
Koh Valerie T J.
Mak Tze M.
Cui Lin.
Lin Raymond V T P.
Heng Derrick.
Leo Yee-Sin.
Lye David C.
Lee Vernon J M.
Kam Kai-qian.
Kalimuddin Shirin.
Tan Seow Yen.
Loh Jiashen.
Thoon Koh Cheng.
Vasoo Shawn.
Khong Wei Xin.
Suhaimi Nur-Afidah.
Chan Sherlynn JH.
Zhang Emma.
Oh Olivia.
Ty Albert.
Tow Charlene.
Chua Yi Xian.
Chaw Wei Liang.
Ng Yixiang.
Abdul-Rahman Farid.
Sahib Shafiq.
Zhao Zheng.
Tang Cheryl.
Low Constance.
Goh Ee Hui.
Lim Georgina.
Hou Yan'an.
Roshan Imran.
Tan James.
Foo Kelly.
Nandar Khine.
Kurupatham Lalitha.
Chan Pei Pei.
Raj Pream.
Lin Yijun.
Said Zubaidah.
Lee Anne.
See Cherie.
Markose Jessey.
Tan Joanna.
Chan Guanhao.
See Wanhan.
Peh Xinyi.
Cai Vincent.
Chen Wen Kai.
Li Zongbin.
Soo Roy.
Chow Angela LP.
Wei Wycliffe.
Farwin Aysha.
Ang Li Wei.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.1016/s0140-6736(20)30528-6
BACKGROUND:Three clusters of coronavirus disease 2019 (COVID-19) linked to a tour group from China, a company conference, and a church were identified in Singapore in February, 2020. METHODS:We gathered epidemiological and clinical data from individuals with confirmed COVID-19, via interviews and inpatient medical records, and we did field investigations to assess interactions and possible modes of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Open source reports were obtained for overseas cases. We reported the median (IQR) incubation period of SARS-CoV-2. FINDINGS:As of Feb 15, 2020, 36 cases of COVID-19 were linked epidemiologically to the first three clusters of circumscribed local transmission in Singapore. 425 close contacts were quarantined. Direct or prolonged close contact was reported among affected individuals, although indirect transmission (eg, via fomites and shared food) could not be excluded. The median incubation period of SARS-CoV-2 was 4 days (IQR 3-6). The serial interval between transmission pairs ranged between 3 days and 8 days. INTERPRETATION:SARS-CoV-2 is transmissible in community settings, and local clusters of COVID-19 are expected in countries with high travel volume from China before the lockdown of Wuhan and institution of travel restrictions. Enhanced surveillance and contact tracing is essential to minimise the risk of widespread transmission in the community. FUNDING:None.
The Lancet
2020
Artículo
http://www.thelancet.com/article/S0140673620305286/pdf
Inglés
VIRUS RESPIRATORIOS
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