Please use this identifier to cite or link to this item:
A recombinant infectious bronchitis virus from a chicken with a spike gene closely related to that of a turkey coronavirus.
Wang Yan.
Cui Xuejiao.
Chen Xu.
Yang Shixing.
Ling Yu.
Song Qianben.
Zhu Su.
Sun Luying.
Li Chuang.
Li Yu.
Deng Xutao.
Delwart Eric.
Zhang Wen.
Acceso Abierto
Using viral metagenomics, the complete genome sequence of an infectious bronchitis virus (IBV) strain (named ahysx-1) from a fecal sample from a healthy chicken in Anhui province, China, was determined. The genome sequence of ahysx-1 was found to be very similar to that of IBV strain ck/CH/LLN/131040 (KX252787), except for the spike gene region, which is similar to that of a turkey coronavirus strain (EU022526), suggesting that ahysx-1 is a recombinant. Recombination analysis and phylogenetic analysis based on the genomic sequences of ahysx-1 and other related strains confirmed that ahysx-1 appears to be a recombinant resulting from a recombination event that occurred between a chicken coronavirus and a turkey coronavirus. Further studies need to be performed to determine whether this recombinant IBV strain is pathogenic and whether it is transmitted between chickens and turkeys.
Archives of virology
Appears in Collections:Artículos científicos

Upload archives

File SizeFormat 
1108062.pdf1.78 MBAdobe PDFView/Open