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Diabetes is a risk factor for the progression and prognosis of COVID-19
Guo Weina.
Li Mingyue.
Dong Yalan.
Zhou Haifeng.
Zhang Zili.
Tian Chunxia.
Qin Renjie.
Wang Haijun.
Shen Yin.
Du Keye.
Zhao Lei.
Fan Heng.
Luo Shanshan.
Hu Desheng.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.1002/dmrr.3319
BACKGOUND:To figure out whether diabetes is a risk factor influencing the progression and prognosis of 2019 novel coronavirus disease (COVID-19). METHODS:A total of 174 consecutive patients confirmed with COVID-19 were studied. Demographic data, medical history, symptoms and signs, laboratory findings, chest computed tomography (CT) as well the treatment measures were collected and analysed. RESULTS:We found that COVID-19 patients without other comorbidities but with diabetes (n = 24) were at higher risk of severe pneumonia, release of tissue injury-related enzymes, excessive uncontrolled inflammation responses and hypercoagulable state associated with dysregulation of glucose metabolism. Furthermore, serum levels of inflammation-related biomarkers such as IL-6, C-reactive protein, serum ferritin and coagulation index, D-dimer, were significantly higher (P
Diabetes/Metabolism Research and Reviews
2020
Artículo
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/dmrr.3319
Inglés
VIRUS RESPIRATORIOS
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