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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/4898| Mitigation and herd immunity strategy for COVID-19 is likely to fail | |
| Wolfgang Bock. Barbara Adamik. Marek Bawiec. Viktor Bezborodov. Marcin Bodych. Jan Pablo Burgard. Thomas Goetz. Tyll Krueger. Agata Migalska. Barbara Pabjan. Tomasz Ozanski. Ewaryst Rafajlowicz. Wojciech Rafajlowicz,. Ewa Skubalska-Rafajlowicz. Sara Ryfczynska. Ewa Szczurek. Piotr Szymanski. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1101/2020.03.25.20043109 | |
| On the basis of a semi-realistic SIR microsimulation for Germany and Poland, we show that the R0 parameter interval for which the COVID-19 epidemic stays overcritical but below the capacity limit of the health care system to reach herd immunity is so narrow that a successful implementation of this strategy is likely to fail. Our microsimulation is based on official census data and involves household composition and age distribution as the main population structure variables. Outside household contacts are characterised by an out-reproduction number R* which is the only free parameter of the model. For a subcritical domain we compute the time till extinction and prevalence as a function of the initial number of infected individuals and R*. For the Polish city of Wroclaw we also discuss the combined impact of testing coverage and contact reduction. For both countries we estimate R* for disease progression until 20th of March 2020. | |
| www.medrxiv.org | |
| 2020 | |
| Artículo | |
| https://www.medrxiv.org/content/10.1101/2020.03.25.20043109v1.full.pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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| 1107538.pdf | 2.38 MB | Adobe PDF | Visualizar/Abrir |