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COVID-19: Epidemiology, Evolution, and Cross-Disciplinary Perspectives
Sun Jiumeng.
He Wan-Ting.
Wang Lifang.
Lai Alexander.
Ji Xiang.
Zhai Xiaofeng.
Li Gairu.
Suchard Marc A.
Tian Jin.
Zhou Jiyong.
Veit Michael.
Su Shuo.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.1016/j.molmed.2020.02.008
HighlightsThe basic reproductive number (R0) of 2019-nCoV is higher than R0 of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). COVID-19 presents with asymptomatic infections, with potential to propagate and perpetuate this epidemic.2019-nCoV isolated from patients shows limited sequence diversity, suggesting that the interspecies transmission event was very recent and that the source of the virus was focused, possibly a point-source event.The amino acid sequence in the ACE2 receptor responsible for 2019-nCoV binding in farm animals and cats has only a few exchanges compared with the human receptor, suggesting that the species barrier for virus transmission is small.
Trends in Molecular Medicine
2020
Artículo
http://www.cell.com/article/S1471491420300654/pdf
Inglés
VIRUS RESPIRATORIOS
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