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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/4286| SARS-CoV-2: a storm is raging. | |
| SF Pedersen. YC Ho. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1172/JCI137647 | |
| The pandemic coronavirus infectious disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading across the globe. In this issue of the JCI, Chen and colleagues compared the clinical and immunological characteristics between moderate and severe COVID-19. The authors found that respiratory distress on admission is associated with unfavorable outcomes. Increased cytokine levels (IL-6, IL-10, and TNF-α), lymphopenia (in CD4+ and CD8+ T cells), and decreased IFN-γ expression in CD4+ T cells are associated with severe COVID-19. Overall, this study characterized the cytokine storm in severe COVID-19 and provides insights into immune therapeutics and vaccine design. | |
| The Journal of clinical investigation | |
| 2020 | |
| Artículo | |
| http://www.jci.org/articles/view/137647/files/pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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| 1106239.pdf | 1.58 MB | Adobe PDF | Visualizar/Abrir |