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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/4161| Repurposed drugs for treating lung injury in COVID-19 | |
| Bing He. Lana Garmire. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| https://arxiv.org/pdf/2003.14333v1.pdf | |
| Lung injury with severe respiratory failure is the leading cause of death in COVID-19. Inhibition of ACE2 caused by spike protein of (SARS)-CoV-2 is the most plausible mechanism of lung injury in COVID-19. We proposed six candidate drugs, including geldanamycin, panobinostat, trichostatin A, narciclasine, COL-3 and CGP-60474, that could best reverse abnormal gene expression caused by (SARS)-CoV-2-induced inhibition of ACE2 in lung cells, for the promise of treating lung injuries in COVID-19. | |
| arxiv.org | |
| 2020 | |
| Artículo | |
| https://arxiv.org/pdf/2003.14333v1.pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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| 1105930.pdf | 283.85 kB | Adobe PDF | Visualizar/Abrir |