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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/4034| Phylogenetic network analysis of SARS-CoV-2 genomes. | |
| P Forster. L Forster. C Renfrew. M Forster. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1073/pnas.2004999117 | |
| In a phylogenetic network analysis of 160 complete human severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) genomes, we find three central variants distinguished by amino acid changes, which we have named A, B, and C, with A being the ancestral type according to the bat outgroup coronavirus. The A and C types are found in significant proportions outside East Asia, that is, in Europeans and Americans. In contrast, the B type is the most common type in East Asia, and its ancestral genome appears not to have spread outside East Asia without first mutating into derived B types, pointing to founder effects or immunological or environmental resistance against this type outside Asia. The network faithfully traces routes of infections for documented coronavirus disease 2019 (COVID-19) cases, indicating that phylogenetic networks can likewise be successfully used to help trace undocumented COVID-19 infection sources, which can then be quarantined to prevent recurrent spread of the disease worldwide. | |
| Proceedings of the National Academy of Sciences of the United States of America | |
| 2020 | |
| Artículo | |
| https://www.pnas.org/content/pnas/early/2020/04/07/2004999117.full.pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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