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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/403| SOCRATES: An online tool leveraging a social contact data sharing initiative to assess mitigation strategies for COVID-19 | |
| Philippe Beutels Pietro Coletti Thang Van Hoang Sebastian Funk Lander Willem Niel Hens | |
| Novel Coronavirus | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1101/2020.03.03.20030627 | |
| Objective: Establishing a social contact data sharing initiative and an interactive tool to assess mitigation strategies for COVID-19. Results: We organized data sharing of published social contact surveys via online repositories and formatting guidelines. We analyzed this social contact data in terms of weighted social contact matrices, next generation matrices, relative incidence and R0. We incorporated location-specific isolation measures (e.g. school closure or telework) and capture their effect on transmission dynamics. All methods have been implemented in an online application based on R Shiny and applied to COVID-19 with age-specific susceptibility and infectiousness. Using our online tool with the available social contact data, we illustrate that social distancing could have a considerable impact on reducing transmission for COVID-19. The effect itself depends on assumptions made about disease-specific characteristics and the choice of intervention(s). Keywords: social contact data, user interface, transmission dynamics, infectious diseases, epidemics, social distancing, behavioral changes, data sharing initiative, open-source, COVID-19 ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement LW gratefully acknowledges funding from the Research Foundation Flanders (Grant number 1234620N). This work is part of a project that has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement 682540-TransMID)(TVH, PC and NH). This work is partially funded by the Epipose project from the European Union's SC1-PHE-CORONAVIRUS-2020 programme (101003688). SF was funded by a Wellcome Trust Senior Research Fellowship (210758/Z/18/Z) ### Author Declarations All relevant ethical guidelines have been followed; any necessary IRB and/or ethics committee approvals have been obtained and details of the IRB/oversight body are included in the manuscript. Yes All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable. Yes All data used in the paper are available on the website: http://www.socialcontactdata.org/ with the detailed links on https://zenodo.org/. R code and data can also be found in https://doi.org/10.5281/zenodo.3706788 <http://www.socialcontactdata.org/> | |
| Cold Spring Harbor Laboratory Press | |
| 2020 | |
| Preimpreso | |
| https://www.medrxiv.org/content/10.1101/2020.03.03.20030627v2 | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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