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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/4017| Association of CT Findings with clinical severity in Patients with COVID-19, a multicenter Cohort observational study | |
| Liu Min. Zhang Hongxia. Yu Nan. Hou Qing. Zhu Li. Li Honglun. Wang Jianguo. Zhang Zhi. Gao Liu. Wang Yimin. Dai Rufen. Guo Xiaojuan. Guo Youmin. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.21203/rs.3.rs-22920/v1 | |
| Background 2019 Novel Coronavirus disease (COVID-19) may cause critical illness including severe pneumonia and acute respiratory distress syndrome. Our purpose is to was to analyze the radiological features of COVID-19 pneumonia and its association with clinical severity. Methods This retrospective study included 212 patients (122 males, Mean age, 45.6 ± 12.8 years) from 10 hospitals. Chest CT, chest X-ray (CXR), clinical and laboratory data at admission and follow-up CT were collected. Chest CT and CXR were reviewed and CT score of the involved lung was calculated. Results 94.3% patients had pneumonia on the baseline CT at admission. The most CT findings were as follows: GGO (140/200), GGO with consolidation (38/200) and consolidation (16/200) most involving the lower lobes with a predilection for the peripheral aspects. The CT score negatively correlated with Lymphocyte count while it positively correlated with C-reactive protein. ROC curve showed an optimal cutoff value of the CT score of 15 had a sensitivity of 70% and a specificity of 96.5% for the prediction of severe status. Series CT showed GGO or consolidation gradually reduced in 52 patients while 6 patients had reticular opacities. 14 patients showed the normal CXR while GGO were found on CT. Conclusion COVID-19 pneumonia manifests as focal, multifocal ground-glass opacities with/without consolidations. Higher CT score correlated severe clinical status. CXR is yet insufficient for evaluation of COVID-19 pneumonia. | |
| assets.researchsquare.com | |
| 2020 | |
| Artículo | |
| https://assets.researchsquare.com/files/rs-22920/v1/manuscript.pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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| 1105666.pdf | 3.4 MB | Adobe PDF | Visualizar/Abrir |