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Case- fatality rate in COVID- 19 patients: A meta-analysis of publicly accessible database
Souvik Maitra.
Mansij Biswas.
Sulagna Bhattacharjee.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.1101/2020.04.09.20059683
A novel coronavirus was reported in Wuhan, China in December 2019 to cause severe acute respiratory symptoms (COVID- 19). In this meta-analysis, we estimated case fatality rate from COVID- 19 infection by random effect meta-analysis model with country level data. Publicly accessible web database WorldOMeter (https://www.worldometers.info/coronavirus/) was accessed on 24th March 2020 GMT and reported total number of cases, total death, active cases and seriously ill/ critically ill patients were retrieved. Primary outcome of this meta-analysis was case fatality rate defined by total number of deaths divided by total number of diagnosed cases. Pooled case fatality rate (95% CI) was 1.78 (1.34- 2.22) %. Between country heterogeneity was 0.018 (p<0.0001). Pooled estimate of composite poor outcome (95% CI) was 4.06 (3.24- 4.88) % at that point of time after exclusion of countries reported small number of cases. Pooled mortality rate (95% CI) was 33.97 (27.44- 40.49) % amongst closed cases (where patients have recovered or died) with. Meta regression analysis identified statistically significant association between health expenditure and mortality amongst closed cases (p=0.037).
www.medrxiv.org
2020
Artículo
https://www.medrxiv.org/content/10.1101/2020.04.09.20059683v2.full.pdf
Inglés
VIRUS RESPIRATORIOS
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