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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/3425| Plasma Metabolomic and Lipidomic Alterations Associated with COVID-19 | |
| Wu Di. Shu Ting. Yang Xiaobo. Song Jian-Xin. Zhang Mingliang. Wen Liu. Huang Muhan. Yu Yuan. Yang Qingyu. Zhu Tingju. Xu Jiqian. Mu Jingfang. Wang Yaxin. Wang Hong. Tang Tang. Ren Yujie. Wu Yongran. Qiu Yang. Zhang Ding-Yu. Shang You. Zhou Xi. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1101/2020.04.05.20053819 | |
| The pandemic of the coronavirus disease 2019 (COVID-19) has become a global public health crisis. COVID-19 is marked by its rapid progression from mild to severe conditions, particularly in the absence of adequate medical care. However, the physiological changes associated with COVID-19 are barely understood. In this study, we performed untargeted metabolomic and lipidomic analyses of plasma from a cohort of COVID-19 patients who had experienced different symptoms. We found the metabolite and lipid alterations exhibit apparent correlation with the course of disease in these COVID-19 patients, indicating that the development of COVID-19 affected patient metabolism. Moreover, many of the metabolite and lipid alterations, particularly ones associated with hepatic functions, have been found to align with the progress and severity of COVID-19. This work provides valuable knowledge about blood biomarkers associated with COVID-19 and potential therapeutic targets, and presents important resource for further studies of COVID-19 pathogenesis. | |
| www.medrxiv.org | |
| 2020 | |
| Artículo | |
| https://www.medrxiv.org/content/medrxiv/early/2020/04/07/2020.04.05.20053819.full.pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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