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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/3106| The phenotypic changes of γδ T cells in COVID-19 patients | |
| Lei Lei. Qian Hongbo. Yang Xiaofeng. Zhou Xiaobo. Zhang Xingzhe. Zhang Dan. Dai Tongxin. Guo Rui. Shi Lin. Cheng Yanbin. Zhang Baojun. Hu Jinsong Hu. Guo Yaling. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1101/2020.04.05.20046433 | |
| A novel pneumonia-associated respiratory syndrome named coronavirus disease-2019 (COVID-19), which caused by SARS-CoV-2 and broken in Wuhan, China in the end of 2019. Unfortunately, there is no specific antiviral agent or vaccine available to treat SARS-CoV-2 infections. Also, information regarding the immunological characteristics in COVID-19 patients remains limited. Here we collected the blood samples from 18 healthy donors (HD) and 38 COVID-19 patients to analyze changes in γδ T cells. In comparison to HD, the γδ T cells percentage was decreased. γδ T cells are able to immediately respond to SARS-CoV-2 infection and upregulate the activation marker CD25. In addition, the increased expression of CD4 in γδ T cells may serve as a biomarker for the assessment of SARS-CoV-2 infection. | |
| www.medrxiv.org | |
| 2020 | |
| Artículo | |
| https://www.medrxiv.org/content/medrxiv/early/2020/04/07/2020.04.05.20046433.full.pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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