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COVID-19 – Considerations for the paediatric rheumatologist | |
Hedrich Christian M.. | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
10.1016/j.clim.2020.108420 | |
The novel coronavirus SARS-CoV2 is a threat to the health and well-being of millions of lifes across the globe. A significant proportion of adult patients require hospitalisation and may develop severe life-threatening complications. Children, on the other hand, can carry and transmit the virus, but usually do not develop severe disease. Mortality in the paediatric age-group is relatively low. Differences in virus containment and clearance, as well as reduced inflammation-related tissue and organ damage may be caused by age-specific environmental and host factors. Since severe complications in adults are frequently caused by uncontrolled immune responses and a resulting "cytokine storm" that may be controlled by targeted blockade of cytokines, previously established treatment with immunosuppressive treatments may indeed protect children from complications. | |
Clinical Immunology | |
2020 | |
Artículo | |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151358/pdf/main.pdf | |
Inglés | |
VIRUS RESPIRATORIOS | |
Aparece en las colecciones: | Artículos científicos |
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