Please use this identifier to cite or link to this item: https://covid-19.conacyt.mx/jspui/handle/1000/2972
Presymptomatic Transmission of SARS-CoV-2 - Singapore, January 23-March 16, 2020.
WE Wei.
Z Li.
CJ Chiew.
SE Yong.
MP Toh.
VJ Lee.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.15585/mmwr.mm6914e1
Presymptomatic transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), might pose challenges for disease control. The first case of COVID-19 in Singapore was detected on January 23, 2020, and by March 16, a total of 243 cases had been confirmed, including 157 locally acquired cases. Clinical and epidemiologic findings of all COVID-19 cases in Singapore through March 16 were reviewed to determine whether presymptomatic transmission might have occurred. Presymptomatic transmission was defined as the transmission of SARS-CoV-2 from an infected person (source patient) to a secondary patient before the source patient developed symptoms, as ascertained by exposure and symptom onset dates, with no evidence that the secondary patient had been exposed to anyone else with COVID-19. Seven COVID-19 epidemiologic clusters in which presymptomatic transmission likely occurred were identified, and 10 such cases within these clusters accounted for 6.4% of the 157 locally acquired cases. In the four clusters for which the date of exposure could be determined, presymptomatic transmission occurred 1-3 days before symptom onset in the presymptomatic source patient. To account for the possibility of presymptomatic transmission, officials developing contact tracing protocols should strongly consider including a period before symptom onset. Evidence of presymptomatic transmission of SARS-CoV-2 underscores the critical role social distancing, including avoidance of congregate settings, plays in controlling the COVID-19 pandemic.
MMWR. Morbidity and mortality weekly report
2020
Artículo
https://www.cdc.gov/mmwr/volumes/69/wr/pdfs/mm6914e1-H.pdf
Inglés
VIRUS RESPIRATORIOS
Appears in Collections:Artículos científicos

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