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Mortality of a pregnant patient diagnosed with COVID-19: A case report with clinical, radiological, and histopathological findings | |
Karami Parisa. Naghavi Maliheh. Feyzi Abdolamir. Aghamohammadi Mehdi. Novin Mohammad Sadegh. Mobaien Ahmadreza. Qorbanisani Mohamad. Karami Aida. Norooznezhad Amir Hossein. | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
10.1016/j.tmaid.2020.101665 | |
This report highlights details on a pregnant case of COVID-19 who unfortunately did not survive. This 27-year-old woman at her 30 and 3/7 weeks' gestation was referred to our center with fever, myalgia, and cough. The laboratory investigations showed leukopenia and lymphopenia as well as increased creatinine and CRP levels. The first chest X-ray (faint bilateral patchy opacities) and CT scan (some faint subpleural ground-glass opacities associated with pleural thickening) were not typical for initial COVID-19 pulmonary infection, however, the treatment for COVID-19 was started. Due to respiratory distress, she was intubated and put under mechanical ventilation. After a while, the fetus was born with Apgar score of 0 and did not react to the neonatal cardiopulmonary resuscitation protocol. Finally, due to deterioration in the clinical and imaging findings, the patient was expired as a result of multi-organ failure. Following the death, autopsy was performed and the histopathologic evaluations of the lungs showed evidence of viral pneumonia (viral cytopathic effect and a mild increase in alveolar wall thickness) and ARDS (hyaline membrane). Also, reverse transcription-polymerase chain reaction (RT-PCR) confirmed SARS-CoV-2 infection in the lungs. To our knowledge, this is the first report of maternal death with confirmed COVID-19 infection. | |
Travel Medicine and Infectious Disease | |
2020 | |
Artículo | |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151464/pdf/main.pdf | |
Inglés | |
VIRUS RESPIRATORIOS | |
Aparece en las colecciones: | Artículos científicos |
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