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Mortality of a pregnant patient diagnosed with COVID-19: A case report with clinical, radiological, and histopathological findings
Karami Parisa.
Naghavi Maliheh.
Feyzi Abdolamir.
Aghamohammadi Mehdi.
Novin Mohammad Sadegh.
Mobaien Ahmadreza.
Qorbanisani Mohamad.
Karami Aida.
Norooznezhad Amir Hossein.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.1016/j.tmaid.2020.101665
This report highlights details on a pregnant case of COVID-19 who unfortunately did not survive. This 27-year-old woman at her 30 and 3/7 weeks' gestation was referred to our center with fever, myalgia, and cough. The laboratory investigations showed leukopenia and lymphopenia as well as increased creatinine and CRP levels. The first chest X-ray (faint bilateral patchy opacities) and CT scan (some faint subpleural ground-glass opacities associated with pleural thickening) were not typical for initial COVID-19 pulmonary infection, however, the treatment for COVID-19 was started. Due to respiratory distress, she was intubated and put under mechanical ventilation. After a while, the fetus was born with Apgar score of 0 and did not react to the neonatal cardiopulmonary resuscitation protocol. Finally, due to deterioration in the clinical and imaging findings, the patient was expired as a result of multi-organ failure. Following the death, autopsy was performed and the histopathologic evaluations of the lungs showed evidence of viral pneumonia (viral cytopathic effect and a mild increase in alveolar wall thickness) and ARDS (hyaline membrane). Also, reverse transcription-polymerase chain reaction (RT-PCR) confirmed SARS-CoV-2 infection in the lungs. To our knowledge, this is the first report of maternal death with confirmed COVID-19 infection.
Travel Medicine and Infectious Disease
2020
Artículo
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151464/pdf/main.pdf
Inglés
VIRUS RESPIRATORIOS
Aparece en las colecciones: Artículos científicos

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