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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/2487| Relationship between COVID-19 death toll doubling time and national BCG vaccination policy | |
| Yutaka Akiyama. Takashi Ishida. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1101/2020.04.06.20055251 | |
| In this manuscript, we showed a statistically significant difference of the doubling times of the death toll between the group of countries with national universal Bacillus Calmette-Guerin (BCG) vaccination and the group without it for recent years. Based on a statistical test, the distributions of the doubling time of these two groups were significantly different (p=0.004). Miller et al. reported the relationship between BCG vaccination and mortality for COVID-19 based on deaths per million inhabitants. However, they did not take into account the differences in COVID-19 detection rates among the countries and the epidemic stages of the countries. Therefore we used a doubling time of the death toll as a more stable indicator instead. We also investigated the dependency of the BCG strains. Among the 32 BCG-vaccinated countries, the median doubling time of the four countries using "Tokyo 172-1" strain (Japan, Iraq, Malaysia, and Pakistan) was 6.8, and that of the other 28 vaccinated countries was 3.8. Their distributions were also significantly different (p=0.024). | |
| www.medrxiv.org | |
| 2020 | |
| Artículo | |
| https://www.medrxiv.org/content/10.1101/2020.04.06.20055251v2.full.pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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