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A Flexible Genome-Scale Resource of SARS-CoV-2 Coding Sequence Clones
Kim Dae-Kyum.
Knapp Jennifer.
Kuang Da.
Cassonnet Patricia.
Samavarchi-Tehrani Payman.
Abdouni Hala.
Rayhan Ashyad.
Sheykhkarimli Dayag.
Coyaud Etienne.
van der Werf Sylvie.
Demeret Caroline.
Gingras Anne-Claude.
Raught Brian.
Jacob Yves.
Roth Frederick.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.20944/preprints202004.0009.v1
The world is facing a major health crisis, the global pandemic of COVID-19 caused by the SARS-CoV-2 coronavirus, for which no approved antiviral agents or vaccines are currently available. Here we describe a collection of codon-optimized coding sequences for SARS-CoV-2 cloned into Gateway-compatible entry vectors, which enable rapid transfer into a variety of expression and tagging vectors. The collection is freely available via Addgene. We hope that widespread availability of this SARS-CoV-2 resource will enable many subsequent molecular studies to better understand the viral life cycle and how to block it.
www.preprints.org
2020
Artículo
https://www.preprints.org/manuscript/202004.0009/v1/download
Inglés
VIRUS RESPIRATORIOS
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