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Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19) | |
Giudicessi John R.. Noseworthy Peter A.. Friedman Paul A.. Ackerman Michael J.. | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
10.1016/j.mayocp.2020.03.024 | |
As the coronavirus disease 19 (COVID-19) global pandemic rages across the globe, the race to prevent and treat this deadly disease has led to the “off-label” repurposing of drugs such as hydroxychloroquine and lopinavir/ritonavir, which has the potential for unwanted QT-interval prolongation and a risk of drug-induced sudden cardiac death. With the possibility that a considerable proportion of the world’s population soon could receive COVID-19 pharmacotherapies with torsadogenic potential for therapy or postexposure prophylaxis, this document serves to help health care professionals mitigate the risk of drug-induced ventricular arrhythmias while minimizing risk of COVID-19 exposure to personnel and conserving the limited supply of personal protective equipment. | |
Mayo Clinic Proceedings | |
2020 | |
Artículo | |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141471/pdf/main.pdf | |
Inglés | |
VIRUS RESPIRATORIOS | |
Aparece en las colecciones: | Artículos científicos |
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