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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/2048| Evaluation of heating and chemical protocols for inactivating SARS-CoV-2 | |
| Boris Pastorino. Franck Touret. Magali Gilles. Xavier de Lamballerie. Remi N Charrel. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1101/2020.04.11.036855 | |
| Clinical samples collected in COVID-19 patients are commonly manipulated in BSL-2 laboratories for diagnostic purpose. We used the French norm NF-EN-14476+A2 derived from the European standard EN-14885. To avoid the risk of exposure of laboratory workers, we showed that Sodium-dodecyl-sulfate and Triton-X100 must be added to guanidinium thiocyanate-lysis buffers to obtain a 6-log reduction of infectious virus. Heating protocol consisting of 92{degrees}C-15min was more effective rather than 56{degrees}C-30min and 60{degrees}C-60min to achieve 6-log reduction. | |
| www.biorxiv.org | |
| 2020 | |
| Artículo | |
| https://www.biorxiv.org/content/10.1101/2020.04.11.036855v2.full.pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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