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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/1921| The BathRC model: a method to estimate flow restrictor size for dual ventilation of dissimilar patients | |
| Andrew R Plummer. Jonathan l du Bois. Siu Man Lee. Patrick Magee. Jens Roesner. Harinderjit S Gill. | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1101/2020.04.12.20062497 | |
| With large numbers of COVID-19 patients requiring mechanical ventilation and ventilators being in short supply, in extremis two patients are having to share one ventilator. This possibility has been discussed for at least two decades, and careful matching of patient ventilation requirements is advised. However, with a large range of lung compliance and other characteristics, which may also vary with time, good matching is difficult to achieve. Adjusting the impedance of the flow path between ventilator and patient gives the opportunity to control the airway pressure and hence flow and volume individually for each patient. Several groups are now investigating this, in particular the addition of a flow restrictor in the inspiration tube for the patient who is more compliant, or requires a lower tidal volume. In this paper, we show that a simple linear resistance-compliance model, termed the BathRC model, of the ventilator tubing system and lung allows direct calculation of the relationships between pressures, volumes, and required flow restriction. The BathRC model is experimentally validated using a GE Aisys CS2 ventilator connected to two test lungs. The pressure-flow relationships for two restrictors are experimentally determined, and despite the need to approximate them with a linear resistance characteristic, their effect in the breathing circuit is accurately predicted by the simple model. The BathRC model is freely available for download; we do not condone dual ventilation, but this tool is provided to demonstrate that flow restriction can be readily estimated. This research is part of a larger test, simulation and design investigation on dual ventilation being undertaken at the UoB and RUH. | |
| www.medrxiv.org | |
| 2020 | |
| Artículo | |
| https://www.medrxiv.org/content/10.1101/2020.04.12.20062497v1.full.pdf | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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| 1100491.pdf | 1.43 MB | Adobe PDF | Visualizar/Abrir |