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Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach
Raj Sibi.
Chandel Vaishali.
Rathi Brijesh.
Kumar Dhruv.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.20944/preprints202004.0285.v1
In December 2019, outbreak of novel coronavirus (COVID-19) occurred in Wuhan, Hubei Province, China and exported across the world leading to thousands of deaths and millions of suspected cases. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection into the host undergoes a huge number of complex replicative machineries which still remains unclear. Understanding the mechanism (s) of replication and mode of infection of SARS-CoV2 to human cells will help us in the development of novel vaccines or drugs for the eradication and prevention of the disease. This review compiles the knowledge of SARS-CoV2 replicative machinery, mode of infection to the human cells and the development of drugs and vaccines which are currently under clinical trials.
www.preprints.org
2020
Artículo
https://www.preprints.org/manuscript/202004.0285/v1/download
Inglés
VIRUS RESPIRATORIOS
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