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Clinical course and characteristics of Corona Virus Disease 2019 in Xiaoshan, Hangzhou: A Retrospective study
Lai Fenhua.
Zheng Yongtao.
Jia Hexiang.
Wang Fuliang.
Sun Xiangjue.
Yang Dongbo.
Xu Miaojian.
Xu Diwei.
Lu Chao.
Ge Bo.
Chen Shenglan.
Li Biao.
Chen Ting.
Li Zhibo.
Feng Yuanmei.
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.21203/rs.3.rs-22080/v1
Background: The World Health Organization declared the outbreak a public health emergency of international concern (Corona Virus Disease 2019) on January 30th, this study aimed to investigate the epidemiological and clinical characteristics of Corona Virus Disease 2019 in Xiaoshan, Hangzhou, and evaluate scientific basis for disease control and prevention. Methods: A total of 30 patients had been admitted to hospital from Jan 22 to Feb 22, 2020, all of them were laboratory confirmed SARS-Cov-2. Demographic, epidemiological, clinical, laboratory data were collected from Hospital information system and Epidemiological investigation reports. All data was performed by descriptive analysis, Chi-square test or non-parametric Mann-Whitney U test, as appropriate. Two sided p value less than 0.05 was considered statistically significant.Results: 30 patients were enrolled, the median age was 44.5 years (IQR 33.8-52.3) and 17 (56.7%) patients were female, 14 (46.7%) patients were native and had no exposure to Hubei Province. At the time of study submission, only one patient had not been discharged and no patients died during the study. The median hospital stay was 16.0 days (IQR 12.5-20.5) and the median course of disease was 20.5 days (IQR 17.0-23.3). The most common symptoms were fever (66.7%), dry cough (26.7%), and pharyngalgia (23.3%) on first admission. Most patients were generally illness or more mild, but 10 (33.3%) patients received oxygen therapy and 14 (46.7%) patients received hormone therapy during their hospitalization. Almost half of patients showed mild lymphocytopenia and 40% patients had elevated concentrations of CRP in the early stages of COVID-19.Conclusions: Among the 30 patients were confirmed with SARA-Cov-2 infection in Xiaoshan, Hangzhou, most of them had clinical presentation of respiratory tract infection, but the median course of disease was more than 2 weeks. Further systematic prospective studies about COVID-19 should be urgently needed.
assets.researchsquare.com
2020
Artículo
https://assets.researchsquare.com/files/rs-22080/v1/manuscript.pdf
Inglés
VIRUS RESPIRATORIOS
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