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Human-animal interactions and bat coronavirus spillover potential among rural residents in Southern China
Li, H
Mendelsohn, E
Zong, C
Zhang, W
Hagan, E
Wang, N
Li, S
Yan, H
Huang, H
Zhu, G
Ross, N
Chmura, A
Terry, P
Fielder, M
Miller, M
Shi, Z
Daszak, P
Acceso Abierto
Highlights Scientific question. ∙ What are the behavioral risks in human-animal interactions that could lead to the emergence of bat coronaviruses in human population. Evidence before this study. ∙ Bat borne coronaviruses have caused several emerging infectious disease outbreaks of global significance, including SARS. Novel SARS-related coronaviruses have been discovered in bat populations in Southern China, some of which have the capacity to infect human cells. Human-animal interactions are thought to be critical for the emergence of bat coronaviruses, however the specific interactions linked to animal-to-human spillover remain unknown. New Findings. ∙ This study found serological evidence for bat-borne coronavirus transmission to people. Direct contact with bats was not identified as a risk factor. However, self-reported severe acute respiratory infection (SARI) and/or influenza-like illness (ILI) was linked to human interaction with other wildlife and livestock, suggesting that there may be other zoonotic exposures leading to clinical illness in these populations. Significance of the study. ∙ Findings from this study suggested that an integrated biological and behavioral surveillance in healthy community settings can help identify potential zoonotic disease spillover events or target surveillance to at-risk populations. This approach represents a potential early-warning system that could be used under non-outbreak conditions to identify potential zoonotic emerging diseases prior to largescale outbreaks.
Biosafety and Health
Appears in Collections:Artículos científicos

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